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Psychedelic Definition & Meaning Between 1959 and 1974, a number of studies were reported on the use of LSD to treat children with autism. Typically, after the drug was administered, the children were simply observed and their reactions were recorded in a narrative format. Thus, the resulting data were for the most part qualitative and were presented in a form that was highly subjective, potentially biased by observer expectations, and of unknown reliability and validity. Furthermore, when enthusiastic investigators obtained neutral or negative findings, they often were cast in a more positive light than was warranted. Despite a good number of independent studies, it remains impossible to determine whether LSD had any therapeutic value for children with autism. When judged by today’s standards of randomized controlled trials, or a properly controlled and systematically replicated single-case study, most of the early autism/LSD studies were so flawed as to be little better than an